The glance at the classical anthropological perspectives implies that the concept of ‘region’ was often tied to the environment and used mainly as a comparison unit and there were fewer intentions to try to discover the internal aspects of a ‘region’. The ideas of the contemporary scholars give a new room for the discussions about the connections between different territories, regions, concepts of local/global, homogeneity/heterogeneity, place, space/time etc. Generally, the article strives to prefigure possible ‘framework’ for the concept of ‘region’ and main elements as well as problems of its definition, and its application possibilities in the anthropological studies. The term ‘region’ is often occurring both in everyday and academic languages. But the question is, if it is possible to describe what kind of content is framed within the word ‘region’, because it does not have its own exact definition. Still it is usual to relate the term ‘region’ with geographical terms of various kinds of territories, for example, area, place, site, city etc. The scholarly discussions about globalization, its elements and processes influence perceptions of different territorial units and start questioning their stability and fixity.