Professional activation is an important part of the economy, in particular local and regional authorities. Properly initiated entrepreneurship significantly affects, among other things, the direct development of the region, including local businesses and the investment opportunities of local government units. Improving competitiveness and the socio-economic image of the region can be seen by taking direct economic initiatives (also in cooperation with economic entities and/or scientific research units) and by implementation of innovation, the use of various forms of external financing, but primarily through new jobs and business activity. The aim of the study is an attempt to present the issue of professional activation of disabled people in the former Central Pomeranian province, in the county Słupsk. The study public opinion poll (own questionnaire study) was conducted at the turn of 2013–2014y. Survey was also conducted in Polish and English literature. In the years 2007–2015 local government organizations implemented 7 projects in the region of Słupsk and also activities are constantly supported by District Labour Office (PUP) activation, which provides services to 97 % of respondents.