The article aims to reveal the medics’ approach to night shift work in multiprofile hospitals of Lithuania. The night shift medics’ work and it singularity was analysed in several related and summarized aspects: approach to night shift work as a phenomenon (1), the impact of night shift on the physiological needs, health and family (2), the interface of night shift work with the environment and work organization (3). The differences of approaches of doctors and nurses to night shift work were disclosed in the article.