Author analyzed the ways of overcoming the negative tendency to the degradation of the human capital in the provincial regions of Russia and other countries of the Eastern Europe. It’s shown that the important role in the processes of solving the problem should be played by the technical universities, situated in the small towns of the region. The development of the universities should be carried on according to the specific strategy, which’s goal is a training of the qualified specialists, and to take as the students the local young people, which are going to live and get a job in the region in future. There are also presented a set of requirements for this kind of the strategy, which are based on the idea of the institutional projecting of the University Technopolis.