Kristijonas Donelaitis (1714–1780), poet of Prussian Lithuania of the epoch of Enlightenment, who was first turned into a symbol in the late 19th c., for more than a century has been one of the brightest memory sites in the region. The paper analyzes the contexts in which the symbol was actualized in Prussian Lithuania and Klaipeda Region in the late 19th to the late 20th c. The change in the interpretations of Donelaitis is presented: from the resource for the maintenance of Prussian Lithuanian regional patriotism, a symbolic figure of Lithuanian national culture, to the Sovietization of Donelaitis and his turning into a resource for the maintenance of the Lithuanian national uniqueness within the boundaries of the USSR. The analysis of the meaningful content in which the symbol of Donelaitis functioned and of its symbolic expressions proves that, over all the analyzed period, Donelaitis has been a figure that encouraged not only the convergence of cultures, but also a conflict.